Deep Learning-based Virtual Birefringence Imaging and Staining of Amyloid Deposits in Label-Free Tissue
Citation
YANG, Xilin, Bijie BAI, Yijie ZHANG, Musa AYDIN, Yuzhu LI, Sahan Yoruc SELCUK, Paloma Casteleiro COSTA, Zhen GUO, Gregory A. FISHBEIN, Karine ATLAN, William Dean WALLACE, Nir PILLAR & Aydogan OZCAN. "Deep Learning-based Virtual Birefringence Imaging and Staining of Amyloid Deposits in Label-Free Tissue". 2025 Conference on Lasers and Electro-Optics, CLEO, (2025): AA109_2.Abstract
We present virtual birefringence imaging and staining, enabling label-free detection of amyloid deposits in tissue. By transforming autofluorescence images into virtually-stained brightfield and polarization images, this method enhances the accuracy and speed of amyloidosis diagnosis.
