Deep Learning-based Virtual Birefringence Imaging and Staining of Amyloid Deposits in Label-Free Tissue

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Optical Society of America

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info:eu-repo/semantics/embargoedAccess

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We present virtual birefringence imaging and staining, enabling label-free detection of amyloid deposits in tissue. By transforming autofluorescence images into virtually-stained brightfield and polarization images, this method enhances the accuracy and speed of amyloidosis diagnosis.

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2025 CLEO: Applications and Technology, CLEO-AT 2025

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YANG, Xilin, Bijie BAI, Yijie ZHANG, Musa AYDIN, Yuzhu LI, Sahan Yoruc SELCUK, Paloma Casteleiro COSTA, Zhen GUO, Gregory A. FISHBEIN, Karine ATLAN, William Dean WALLACE, Nir PILLAR & Aydogan OZCAN. "Deep Learning-based Virtual Birefringence Imaging and Staining of Amyloid Deposits in Label-Free Tissue". 2025 CLEO: Applications and Technology, CLEO-AT 2025, CLEO, (2025).

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