Deep Learning-based Virtual Birefringence Imaging and Staining of Amyloid Deposits in Label-Free Tissue

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Institute of Electrical and Electronics Engineers Inc.

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info:eu-repo/semantics/embargoedAccess

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We present virtual birefringence imaging and staining, enabling label-free detection of amyloid deposits in tissue. By transforming autofluorescence images into virtually-stained brightfield and polarization images, this method enhances the accuracy and speed of amyloidosis diagnosis.

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2025 Conference on Lasers and Electro-Optics, CLEO

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YANG, Xilin, Bijie BAI, Yijie ZHANG, Musa AYDIN, Yuzhu LI, Sahan Yoruc SELCUK, Paloma Casteleiro COSTA, Zhen GUO, Gregory A. FISHBEIN, Karine ATLAN, William Dean WALLACE, Nir PILLAR & Aydogan OZCAN. "Deep Learning-based Virtual Birefringence Imaging and Staining of Amyloid Deposits in Label-Free Tissue". 2025 Conference on Lasers and Electro-Optics, CLEO, (2025): AA109_2.

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